Just lost a long post with lots of links, but if you haven't done Windows Updates, or updated Flash Player this month, you need to update both ASAP as there are exploits either in the wild or imminent for both. Search older posts here for pertinent download links.
If you run Firefox, update to either 8.0 or 3.6.24 as both have security fixes. Thunderbird is now also at version 8 with security fixes.
Adobe's "Black Tuesday" patch did not include Flash Player, but the Shockwave Player was updated.
Update iTunes and Apple OS X and iOS devices also if you have them.